KAP1 (TRIM28) Rabbit Polyclonal Antibody

CAT#: TA319808

Rabbit Polyclonal TRIM28 Antibody

Product Images

Western blot analysis of TRIM28 in human testis tissue lysate with TRIM28 antibody at 1 ug/mL.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Rabbit polyclonal TRIM28 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human TRIM28.
• Formulation: TRIM28 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: TRIM28 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 92 kDa
• Gene Name: tripartite motif containing 28
• Database Link:
  NP_005753
  Entrez Gene 21849 MouseEntrez Gene 116698 RatEntrez Gene 10155 Human
  UniProt ID Q13263
• Background: TRIM28 Antibody: TRIM28, also known as KAP-1, is a member of the Transcriptional Intermediary Factor 1 (TIF1) subfamily and contains a RING finger, B box, Coiled coil, PHD/TTC, and bromodomain. TRIM28 is a corepressor for Kruppel-associated box (KRAB)-domain-containing zinc finger proteins and plays a critical role in early embryogenesis. TRIM28 acts as a transcriptional mediator by binding liganded nuclear receptors, including retinoic acid (RAR), retinoid X (RXR) and estrogen (ER) receptors. TRIM28 associates with both heterochromatin and euchromatin, causing gene silencing by both HP1 binding and histone deacetylation.
• Synonyms: KAP1; PPP1R157; RNF96; TF1B; TIF1B

Reference Data

• Protein Families: Protein Kinase, Stem cell - Pluripotency, Transcription Factors