HAX1 Mouse Monoclonal Antibody [Clone ID: 8F9G7]

CAT#: TA319818

Mouse Hax1a Monoclonal Antibody


USD 430.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Clone Name 8F9G7
Applications WB
Recommended Dilution WB: 1 - 2 ug/mL
Reactivities Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Mouse monoclonal Hax1a antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human Hax1a.
Formulation Hax1a Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification Hax1a Monoclonal Antibody is immunoaffinity chromotography purified IgG.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name HCLS1 associated protein X-1
Background Hax1a Monoclonal Antibody: The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting. At least four isoforms of Hax1 are known to exist. This antibody is expected to recognize the longest isoform (Hax1a) as well as the shortest.
Synonyms HCLSBP1; HS1BP1; SCN3
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.