WDR5 Rabbit Polyclonal Antibody

CAT#: TA319832

Rabbit Polyclonal WDR5 Antibody

Product Images

Western blot analysis of WDR5 in 293 cell lysate with WDR5 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

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  Immunofluorescence of WDR5 in 293 cells with WDR5 antibody at 20 ug/mL.

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  Immunocytochemistry of WDR5 in 293 cells with WDR5 antibody at 5 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 5 ug/mL, IF: 5 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: WDR5 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human WDR5.
• Formulation: WDR5 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: WDR5 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: WD repeat domain 5
• Database Link:
  NP_060058
  Entrez Gene 11091 Human
  UniProt ID P61964
• Background: WDR5 Antibody: WD repeat domain 5 (WDR5) is a member of the WD repeat protein family, which is involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WDR5, also known as BIG-3, is expressed in the developing growth plate, accelerates chondrocyte and osteoblast differentiation in vitro, and regulates osteoblast differentiation during embryonic bone development. WDR5 interacts with the pluripotency factor Oct4/POU5F1 and is required for the efficient formation of induced pluripotent stem (iPS) cells.
• Synonyms: BIG-3; CFAP89; SWD3

Reference Data

• Protein Families: Druggable Genome