GABARAP Rabbit Polyclonal Antibody

CAT#: TA319834

Rabbit Polyclonal GABARAP Antibody

Product Images

Western blot analysis of GABARAP in K562 cell lysate with GABARAP antibody at (A) 1 and (B) 2 ug/mL.

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  Immunofluorescence of GABARAP in human brain tissue with GABARAP antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: GABARAP antibody was raised against a 19 amino acid peptide near the amino terminus of human GABARAP.
• Formulation: GABARAP Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: GABARAP Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 13 kDa
• Gene Name: GABA type A receptor-associated protein
• Database Link:
  NP_009209
  Entrez Gene 56486 MouseEntrez Gene 58974 RatEntrez Gene 11337 Human
  UniProt ID O95166
• Background: GABARAP Antibody: Gamma-aminobutyric acid (GABA) is the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing in the central nervous system. It has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. GABARAP (GABAA receptor-associated protein) links GABAA receptors to the cytoskeleton and may play a role in intracellular transport of GABAA receptors and its interaction with the cytoskeleton. GABARAP belongs to the MAP1 or ATG8 like family and recent studies show that MAPK15/ERK8 is acting through interaction with ATG8 family proteins to regulate autophagy.
• Synonyms: ATG8A; GABARAP-a; MM46

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Regulation of autophagy