ANKRD15 (KANK1) Rabbit Polyclonal Antibody

CAT#: TA319847

Rabbit Polyclonal KANK1 Antibody

Product Images

Western blot analysis of KANK1 in 3T3 cell lysate with KANK1 antibody at 1 ug/mL.

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  Immunohistochemistry of KANK1 in human kidney tissue with KANK1 antibody at 2.5 ug/mL.

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  Immunofluorescence of KANK1 in human kidney tissue with KANK1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: KANK1 antibody was raised against a 19 amino acid peptide near the amino terminus of human KANK1 .
• Formulation: KANK1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: KANK1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 149 kDa; Observed: 150 kDa
• Gene Name: KN motif and ankyrin repeat domains 1
• Database Link:
  NP_694856
  Entrez Gene 107351 MouseEntrez Gene 23189 Human
  UniProt ID Q14678
• Background: KANK1 Antibody: Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK1 (KN motif and ankyrin repeat domain-containing protein 1), also known as ANKRD15, is a 1,352 amino acid protein that contains at least 12 exons and 5 ANK repeats. It binds to beta-catenin and regulates its subcellular distribution. KANK1 is ubiquitously expressed and localizes to cytoplasm. It may function as a tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder.
• Synonyms: ANKRD15; CPSQ2; KANK