AP3M1 Rabbit Polyclonal Antibody

CAT#: TA319886

Rabbit Polyclonal AP3M1 Antibody

Product Images

Western blot analysis of AP3M1 in human brain tissue lysate with AP3M1 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunohistochemistry of AP3M1 in mouse brain tissue with AP3M1 antibody at 5 ug/mL.

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  Immunofluorescence of AP3M1 in mouse brain tissue with AP3M1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: AP3M1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human AP3M1.
• Formulation: AP3M1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: AP3M1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: adaptor related protein complex 3 mu 1 subunit
• Database Link:
  NP_036227
  Entrez Gene 55946 MouseEntrez Gene 171126 RatEntrez Gene 26985 Human
  UniProt ID Q9Y2T2
• Background: AP3M1 Antibody: The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3M1 is highly homologous to AP3M2 but is the preferred binding partner to the YQRL motif from the cytosolic domain of TGN38. AP3M1 has also been shown to interact with the HIV-1 virulence protein Nef.
• Synonyms: RP11-178G16.4

Reference Data

• Protein Pathways: Lysosome