CD244 Rabbit Polyclonal Antibody

CAT#: TA319935

Rabbit Polyclonal SLAMF4 Antibody

Product Images

Western blot analysis of SLAMF4 in Daudi cell lysate with SLAMF4 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunofluorescence of SLAMF4 in Daudi cells with SLAMF4 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SLAMF4 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human SLAMF4.
• Formulation: SLAMF4 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: SLAMF4 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: CD244 molecule
• Database Link:
  NP_001160135
  Entrez Gene 18106 MouseEntrez Gene 64025 RatEntrez Gene 51744 Human
  UniProt ID Q9BZW8
• Background: SLAMF4 Antibody: The signaling lymphocyte-activation molecule family member 4 (SLAMF4), also known as 2B4, is an important regulator of Natural Killer (NK) cell activation. It is expressed on NK cells as well as on subsets of T cells and interacts with SLAMF2, causing the activation of both SLAMF4- and SLAMF2-expressing cells. Patients with systemic lupus erythmatosus have lower than normal levels of SLAMF4 expressed on their NK cells and monocytes, suggesting that SLAMF4 may play a role in this autoimmune disease.
• Synonyms: 2B4; NAIL; NKR2B4; Nmrk; SLAMF4

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Natural killer cell mediated cytotoxicity