Lymphocyte Antigen 6 Complex (LY6K) Rabbit Polyclonal Antibody

CAT#: TA319943

Rabbit Polyclonal LY6K Antibody

Product Images

Western blot analysis of LY6K in HeLa cell lysate with LY6K antibody at (A) 1 and (B) 2 ug/mL.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: LY6K antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human LY6K.
• Formulation: LY6K Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: LY6K Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: lymphocyte antigen 6 complex, locus K
• Database Link:
  NP_059997
  Entrez Gene 76486 MouseEntrez Gene 100363492 RatEntrez Gene 54742 Human
  UniProt ID Q17RY6
• Background: LY6K Antibody: The lymphocyte antigen 6 complex locus K (LY6K), a member of cancer-testis antigen was initially identified as a molecular marker for head-and-neck squamous cell carcinoma as well a breast cancer. LY6K is a GPI-anchored membrane protein that is specifically associated with germ cell marker TEX101 and is strongly observed in testis, but only weakly in other tissues. LY6K mRNA was found to be upregulated in numerous bladder cancers due to gene amplification. Furthermore, knockdown experiments using LY6K siRNA reduced cell growth, migration and invasion in bladder carcinoma cell lines, suggesting that LY6K contributes to bladder cancer development.
• Synonyms: CT97; HSJ001348; ly-6K; URLC10

Reference Data

• Protein Families: Transmembrane