RBM35A (ESRP1) Rabbit Polyclonal Antibody

CAT#: TA319945

Rabbit Polyclonal RBM35A Antibody

Product Images

Western blot analysis of RBM35A in rat colon tissue lysate with RBM35A antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide.

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  Immunohistochemistry of RBM35A in human colon tissue with RBM35A antibody at 2.5 ug/mL.

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  Immunofluorescence of RBM35A in human colon tissue cells with RBM35A antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 0.5 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: RBM35A antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of human RBM35A.
• Formulation: RBM35A Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: RBM35A Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: epithelial splicing regulatory protein 1
• Database Link:
  NP_001030087
  Entrez Gene 207920 MouseEntrez Gene 500409 RatEntrez Gene 54845 Human
  UniProt ID Q6NXG1
• Background: RBM35A Antibody: RBM35A, also known as ESRP1, is a mRNA splicing factor that with its related protein RBM35B (ESRP2) are coordinators of an epithelial cell-type-specific splicing program. RBM35A contains three putative RNA recognition motifs and acts by directly binding specific sequences in mRNAs. RBM35A is involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs. Other recent studies have shown that RMB35A may also act as a novel tumor suppressor.
• Synonyms: RBM35A; RMB35A