CASKIN1 Rabbit Polyclonal Antibody

CAT#: TA319979

Rabbit Polyclonal CASKIN1 Antibody

Product Images

Western blot analysis of CASKIN1 in HeLa cell lysate with CASKIN1 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: CASKIN1 antibody was raised against a 17 amino acid synthetic peptide near the center of human CASKIN1.
• Formulation: CASKIN1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: CASKIN1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 157 kDa
• Gene Name: CASK interacting protein 1
• Database Link:
  NP_065815
  Entrez Gene 57524 Human
  UniProt ID Q8WXD9
• Background: CASKIN1 Antibody: Calcium/calmodulin-dependent serine protein kinase (CASK) is a conserved multi-domain scaffolding protein involved in brain development, synapse formation, and establishment of cell polarity. CASKINs (CASK interacting proteins) interact with CASK and is thought to play a role in CASK function, specifically by coupling CASK to distinct downstream effectors. CASKIN1 is a multidomain protein containing six N-terminal ankyrin repeats, one SH3 domain, and two sterile alpha motif domains followed by a long proline-rich sequence and a short conserved C-terminal domain. CASKIN1 coassembles with CASK on the cytoplasmic tail of neurexin 1, suggesting that CASKIN and CASK coat the cytoplasmic tails of neurexins and other cell-surface proteins.
• Synonyms: ANKS5A