ATG9A Rabbit Polyclonal Antibody

CAT#: TA320008

Rabbit Polyclonal ATG9A Antibody

Product Images

Western blot analysis of ATG9A in mouse heart tissue lysate with ATG9A antibody at 1 ug/mL.

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  Immunohistochemistry of ATG9A in human heart tissue with ATG9A antibody at 5 ug/mL.

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  Immunofluorescence of ATG9A in human heart tissue with ATG9A antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: ATG9A antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human ATG9A.
• Formulation: ATG9A Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: ATG9A Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: autophagy related 9A
• Database Link:
  NP_001070666
  Entrez Gene 245860 MouseEntrez Gene 363254 RatEntrez Gene 79065 Human
  UniProt ID Q7Z3C6
• Background: ATG9A Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG9A, a multi-spanning membrane protein localizing to the Golgi apparatus and late endosomes, has been proposed to mediate membrane transport to generate autophagosomes. ATG9A has also been implicated as a regulator of STING (stimulator of interferon genes)-mediated innate immune response.
• Synonyms: APG9L1; mATG9; MGD3208

Reference Data

• Protein Families: Transmembrane