NLRX1 Rabbit Polyclonal Antibody

CAT#: TA320016

Rabbit Polyclonal NOD5 Antibody

Product Images

Western blot analysis of NOD5 in rat spleen tissue cell lysate with NOD5 antibody at (A) 1 and (B) 2 ug/mL.

• 

  Immunohistochemistry of NOD5 in rat spleen tissue with NOD5 antibody at 10 ug/mL.

• 

  Immunofluorescence of NOD5 in rat spleen tissue with NOD5 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: NOD5 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NOD5.
• Formulation: NOD5 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: NOD5 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: NLR family member X1
• Database Link:
  NP_078894
  Entrez Gene 270151 MouseEntrez Gene 315599 RatEntrez Gene 79671 Human
  UniProt ID Q86UT6
• Background: NOD5 Antibody: NOD5, also known as NLRX1, is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD5 localizes to the mitochondrial outer membrane and interacts with the virus-induced signaling adapter protein VISA. Unlike a subset of NOD-like receptors (NLRs) such as NOD1 and NOD2 which trigger pro-inflammatory cascades, and other NLRs that induce the caspase 1 inflammasome in response to immune challenges, NOD5 amplifies NF-κB and JNK pathways by inducing reactive oxygen species production.
• Synonyms: CLR11.3; DLNB26; NOD5; NOD9; NOD26

Reference Data

• Protein Pathways: RIG-I-like receptor signaling pathway