KHDC1 Rabbit Polyclonal Antibody

CAT#: TA320032

Rabbit Polyclonal KHDC1 Antibody

Product Images

Western blot analysis of KHDC1 in rat liver tissue lysate with KHDC1 antibody at (A) 0.5 and (B) 1 ug/mL.

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  Immunohistochemistry of KHDC1 in human liver tissue with KHDC1 antibody at 5 ug/mL.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: KHDC1 antibody was raised against a 15 amino acid peptide near the amino terminus of human KHDC1.
• Formulation: KHDC1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: KHDC1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 18 kDa; Observed: 26 kDa
• Gene Name: KH homology domain containing 1
• Database Link:
  NP_085045
  Entrez Gene 689090 RatEntrez Gene 80759 Human
  UniProt ID Q4VXA5
• Background: KHDC1 Antibody: KHDC1 family members are K-homology (KH) domain-containing RNA binding proteins that are involved in various aspects of RNA metabolism, ranging from transcription to RNA splicing, transportation, translation, and stability (1). KHDC1 is highly expressed in oocytes and interacts with cytoplasmic polyadenylation element-binding protein 1 (CPEB1), a key translational regulator controlling the polyA length of mRNAs (2,3). KHDC1 functions as a global translational repressor and induces apoptosis through an ER-dependent signaling pathway and that the C-terminal putative trans-membrane motif (TMM) is critical for its activities (3,4).
• Synonyms: bA257K9.4; C6orf147; C6orf148; Em:AC019205.8; NDG1

Reference Data

• Protein Families: Transmembrane