NETO1 Rabbit Polyclonal Antibody

CAT#: TA320034

Rabbit Polyclonal NETO1 Antibody

Product Images

Western blot analysis of NETO1 in human lung tissue lysate with NETO1 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunohistochemistry of NETO1 in rat lung tissue with NETO1 antibody at 2.5 ug/mL.

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  Immunofluorescence of NETO1 in rat lung tissue with NETO1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: NETO1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human NETO1.
• Formulation: NETO1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: NETO1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: neuropilin and tolloid like 1
• Database Link:
  NP_694821
  Entrez Gene 246317 MouseEntrez Gene 307206 RatEntrez Gene 81832 Human
  UniProt ID Q8TDF5
• Background: NETO1 Antibody: Neuropilin and tolloid-like protein 1 (NETO1) is involved in the development and/or maintenance of neuronal circuitry. It is a type I transmembrane protein that is expressed in the brain and retina. NETO1 contains one LDL-receptor class A domain and two CUB domains and is either membrane-bound or secreted. It has three alternatively spliced isoforms, the first two of which are retina-specific and the third of which is found in both retina and brain tissue. Furthermore, as an accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR), it regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory.
• Synonyms: BCTL1; BTCL1; neuropilin (NRP) and tolloid (TLL)-like 1; neuropilin- and tolloid-like protein 1; OTTHUMP00000163732

Reference Data

• Protein Families: Druggable Genome, Transmembrane