Solo (SESTD1) Rabbit Polyclonal Antibody

CAT#: TA320072

Rabbit Polyclonal SESTD1 Antibody

Product Images

Western blot analysis of SESTD1 in rat brain tissue lysate with SESTD1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

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  Immunohistochemistry of SESTD1 in human brain tissue with SESTD1 antibody at 5 ug/mL.

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  Immunofluorescence of SESTD1 in Human Brain cells with SESTD1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SESTD1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human SESTD1.
• Formulation: SESTD1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: SESTD1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: SEC14 and spectrin domain containing 1
• Database Link:
  NP_835224
  Entrez Gene 228071 MouseEntrez Gene 295678 RatEntrez Gene 91404 Human
  UniProt ID Q86VW0
• Background: SESTD1 Antibody: SESTD1 was initially identified in mutant zebrafish with defects in the spontaneous contraction and touch response as a novel gene, solo, encoding a protein containing SEC14 and spectrin repeat domains. Other experiments indicated that SESTD1 interacts with the TRPC4 and TRPC5, members of the transient receptor potential channel family, via the TRPC calmodulin- and inositol 1, 4, 5-triphosphate receptor-binding domain and is essential for efficient receptor-mediated activation of TRPC5, suggesting that SESTD1 is a novel regulator of these TRPC proteins.
• Synonyms: SOLO

Reference Data

• Protein Families: Druggable Genome