IL17RE Rabbit Polyclonal Antibody
Other products for "IL17RE"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 1 - 2 ug/mL |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Rabbit polyclonal IL-17RE antibody was raised against a 16 amino acid peptide near the center of human IL-17RE. |
Formulation | IL-17RE Antibody is supplied in PBS containing 0.02% sodium azide. |
Concentration | 1ug/ul |
Purification | IL-17RE Antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 78 kDa |
Gene Name | interleukin 17 receptor E |
Database Link | |
Background | IL-17RE Antibody: The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner. |
Synonyms | FLJ23658; interleukin 17 receptor E; MGC71884; OTTHUMP00000158822 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
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