NLRP7 Rabbit Polyclonal Antibody

CAT#: TA320136

Rabbit Polyclonal NALP7 Antibody


USD 430.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution WB: 1 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen NALP7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human NALP7.
Formulation NALP7 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification NALP7 Antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name NLR family, pyrin domain containing 7
Background NALP7 Antibody: NOD proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins. NALP7, also known as PYPAF3, a member of the related PYRIN-containing APAF1-like proteins (PYPAFs/NALPs) is thought to play a crucial role in cell proliferation. NALP7 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It is expressed in numerous tissues including uterus and ovary, with low levels in heart and brain. NALP7 inhibits caspase-1-dependent interleukin-1β secretion and is a feedback regulator of interleukin-1β secretion. Defects in the NALP7 gene are known to cause the formation of a hydatidiform mole (HYDM) and reduce the growth of carcinoma cell lines.
Synonyms CLR19.4; HYDM; NALP7; NOD12; PAN7; PYPAF3
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.