NSE2 (NSMCE2) Rabbit Polyclonal Antibody

CAT#: TA320164

Rabbit Polyclonal MMS21 Antibody

Product Images

Western blot analysis of MMS21 in 293 cell lysate with MMS21 antibody at (A) 0.5 and (B) 1 ug/mL.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5 - 1 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: MMS21 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human MMS21.
• Formulation: MMS21 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: MMS21 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase
• Database Link:
  NP_775956
  Entrez Gene 68501 MouseEntrez Gene 299957 RatEntrez Gene 286053 Human
  UniProt ID Q96MF7
• Background: MMS21 Antibody: MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression; this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.
• Synonyms: C8orf36; MMS21; NSE2; ZMIZ7