NLRP10 Rabbit Polyclonal Antibody

CAT#: TA320167

Rabbit Polyclonal NALP10 Antibody

Product Images

Western blot analysis of NALP10 in human brain tissue lysate with NALP10 antibody at 1 ug/mL.

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  Immunohistochemistry of NALP10 in human brain tissue with NALP10 antibody at 10 ug/mL.

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  Immunofluorescence of NALP10 in human brain tissue with NALP10 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: NALP10 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NALP10.
• Formulation: NALP10 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: NALP10 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: NLR family, pyrin domain containing 10
• Database Link:
  NP_789791
  Entrez Gene 338322 Human
  UniProt ID Q86W26
• Background: NALP10 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1β, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1β processing, and ASC aggregation. NALP10 is thus a potent regulator of apoptosis and inflammation.
• Synonyms: CLR11.1; NALP10; NOD8; PAN5; PYNOD