PIWIL3 Rabbit Polyclonal Antibody

CAT#: TA320190

Rabbit Polyclonal PIWI-L3 Antibody

Product Images

Western blot analysis of PIWI-L3 in 3T3 cell lysate with PIWI-L3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

• 

  Immunofluorescence of PIWI-L3 in 3T3 cells with PIWI-L3 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: PIWI-L3 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human PIWI-L3.
• Formulation: PIWI-L3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: PIWI-L3 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: piwi like RNA-mediated gene silencing 3
• Database Link:
  NP_001008496
  Entrez Gene 440822 Human
  UniProt ID Q7Z3Z3
• Background: PIWI-L3 Antibody: PIWI-L3 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. Recent studies have shown that overexpression of PIWI-L3 (as well as other PIWI-like proteins) are potential biomarkers for astrocytic glioma, meningioma, and other cancers.
• Synonyms: HIWI3

Reference Data

• Protein Pathways: Dorso-ventral axis formation