BCAR1 Goat Polyclonal Antibody

CAT#: TA320209

Goat Polyclonal BCAR1 Antibody

Product Images

Anti-BCAR1 (1ug/ml) staining of MCF7 (A) and Human Breast cancer (B) lysates (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1-3ug/ml, ELISA: 1:128,000
• Reactivities: Human
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-KQTSTFSKQTPHH, from the internal region of the protein sequence according to NP_001164185.1; NP_001164186.1; NP_001164187.1; NP_001164188.1; NP_001164189.1; NP_055382.2; NP_001164190.1; NP_001164191.1; NP_001164192.1
• Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 97.9 kDa
• Gene Name: BCAR1, Cas family scaffolding protein
• Database Link:
  NP_055382
  Entrez Gene 12927 MouseEntrez Gene 25414 RatEntrez Gene 479648 DogEntrez Gene 9564 Human
  UniProt ID P56945
• Background: BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion (Sawada et al., 2006 [PubMed 17129785]). [supplied by OMIM]
• Synonyms: CAS; CAS1; CASS1; CRKAS; P130Cas

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Chemokine signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Regulation of actin cytoskeleton