Ccr5 Hamster Monoclonal Antibody [Clone ID: HM-CCR5 (7A4)]

CAT#: TA320231

Hamster Anti-Mouse CD195 (CCR5) Purified (100 ug)

Specifications

Product Data

• Clone Name: HM-CCR5 (7A4)
• Recommended Dilution: Flow
• Reactivities: Mouse
• Host: Hamster
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: chemokine (C-C motif) receptor 5
• Database Link:
  NP_034047
  Entrez Gene 12774 Mouse
  UniProt ID P51682
• Background: CCR5 is the major co-receptor for macrophage-tropic isolates of HIV-1. CCR5, also known as CD195, is a seven transmembrane chemokine receptor capable of binding RANTES, MIP-1 alpha and MIP-1 beta. Knockout mice show a decreased recruitment of macrophages and increased susceptibility to infection. Protein and mRNA has been found in macrophages from thioglycolate-treated and activated T cells. The HM-CCR5(7A4) monoclonal antibody binds the N terminal extracellular domain of mouse CCR5 with no crossreactivity to human CCR5.
• Synonyms: CC-CKR-5; CCCKR5; CCR-5; CD195; chemr13; CKR-5; CKR5; CMKBR5; FLJ78003; IDDM22; OTTHUMP00000209784