Cd38 Rat Monoclonal Antibody [Clone ID: 90]

CAT#: TA320266

Rat Anti-Mouse CD38 Purified (100 ug)

Product Images

Staining of BALB/c splenocytes with 0.06 ug of Rat IgG2a Isotype Control Purified (open histogram) or 0.06 ug Anti-Mouse CD38 Purified (filled histogram) followed by Anti-Rat IgG FITC. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: 90
• Applications: FC
• Recommended Dilution: Flow, IHC, Functional Assay
• Reactivities: Mouse
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: CD38 antigen
• Database Link:
  NP_031672
  Entrez Gene 12494 Mouse
  UniProt ID P56528
• Background: The 90 monoclonal antibody reacts with the mouse CD38 molecule, an ~42 kDa type II transmembrane protein. CD38 is expressed at increasingly higher levels on B cells at each stage of B-cell differentiation, and is then down-regulated on germinal center B cells and mature plasma cells. Its expression is reported on a subpopulation of thymocytes, mature T cells, and NK cells. Crosslinking of CD38 on the surface of mature, resting B cells induces B-cell proliferation, which is enhanced by co-signals such as IL-4 and LPS. CD38, a counter-receptor for CD31, is an ectoenzyme with cyclase and hydrolase enzymatic activity and is speculated to play a role in lymphocyte activation and differentiation.
• Synonyms: T10