CD3D Mouse Monoclonal Antibody [Clone ID: B1.1]

CAT#: TA320268

Mouse Anti-Human gamma delta TCR Purified (100 ug)

Product Images

Surface staining of normal human peripheral blood cells with Anti-Human gamma delta TCR FITC (left) or PE (right). Appropriate isotype controls were used (open histogram). Cells in the lymphocyte gate were used for analysis.

Specifications

Product Data

• Clone Name: B1.1
• Applications: FC
• Recommended Dilution: Flow
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: CD3d molecule
• Database Link:
  NP_000723
  Entrez Gene 915 Human
  UniProt ID P04234
• Background: The B1.1 monoclonal antibody reacts with the human gamma delta TCR complex. The gamma delta TCR is expressed by a small subset of T cells in the thymus, peripheral lymphoid tissues, intestinal epithelium, and epidermis. The exact specificity, ligand and function of gamma delta TCR-bearing T cells are not yet fully understood; it is suggested that these cells recognize bacterial ligands and some tumor cells in the context of MHC class I-like gene products and play a role in regulation of the immune response and during bacterial infection. This monoclonal can be used as a phenotypic marker for gamma delta TCR-expressing T cells.
• Synonyms: CD3-DELTA; IMD19; T3D

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway