Cd3e Hamster Monoclonal Antibody [Clone ID: 145-2C11]

CAT#: TA320270

Hamster Anti-Mouse CD3e Purified (500 ug)

Product Images

Staining of C57Bl/6 splenocytes with Armenian Hamster IgG Isotype Control Purified (open histogram) or Anti-Mouse CD3e Purified (filled histogram) followed by Anti-Armenian Hamster IgG FITC. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: 145-2C11
• Applications: FC
• Recommended Dilution: Flow, IHC, Functional Assay, IP, WB
• Reactivities: Mouse
• Host: Hamster
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: CD3 antigen, epsilon polypeptide
• Database Link:
  NP_031674
  Entrez Gene 12501 Mouse
  UniProt ID P22646
• Background: The 145-2C11 monoclonal antibody reacts with mouse CD3e, a 20 kDa subunit of the TCR complex. Along with the other CD3 subunits, gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Binding of 145-2C11 to TCR initiates the intracellular biochemical pathway resulting in cellular activation, proliferation, and apoptosis depending on specific conditions utilized. 145-2C11 is commonly used as a phenotypic marker for mouse T cells.
• Synonyms: CD3-epsilon; FLJ18683; T3E; TCRE