CD3E Mouse Monoclonal Antibody [Clone ID: UCHT1]

CAT#: TA320273

Mouse Anti-Human CD3 Purified (100 ug)


USD 185.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Clone Name UCHT1
Applications FC
Recommended Dilution Flow, IHC, Functional Assay
Reactivities Human
Host Mouse
Clonality Monoclonal
Formulation Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration lot specific
Purification Affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name CD3e molecule
Background The UCHT1 monoclonal antibody reacts with human CD3e, a 20 kDa subunit of the TCR complex. Along with the other CD3 subunits gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR via immobilized UCHT1 initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.
Synonyms IMD18; T3E; TCRE
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.