Cd4 Rat Monoclonal Antibody [Clone ID: RM4-5]

CAT#: TA320276

Rat Anti-Mouse CD4 Purified (100 ug)

Product Images

Staining of C57Bl/6 splenocytes with 0.25 ug of Rat IgG2a Isotype Control Purified (open histogram) or 0.25 ug of Anti-Mouse CD4 Purified (filled histogram) followed by Anti-Rat IgG FITC. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: RM4-5
• Applications: FC
• Recommended Dilution: Flow, IHC, Functional Assay
• Reactivities: Mouse
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: CD4 antigen
• Database Link:
  NP_038516
  Entrez Gene 12504 Mouse
  UniProt ID P06332
• Background: The RM4-5 monoclonal antibody reacts with the mouse CD4 molecule, a 55 kDa cell surface receptor expressed by a majority of thymocytes, subpopulation of mature T cells and dendritic cells. CD4 binds to MHC class II on the surface of antigen presenting cells and plays an important role both in T cell development and in optimal functioning of mature T cells. In T cells, CD4 associates with protein tyrosine kinase p56lck through its cytoplasmic tail. Binding of RM4-5 is blocked by GK1.5.
• Synonyms: CD4mut