CD55 Mouse Monoclonal Antibody [Clone ID: 143-30]
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Specifications
Product Data | |
Clone Name | 143-30 |
Recommended Dilution | Flow |
Reactivities | Human |
Host | Mouse |
Clonality | Monoclonal |
Formulation | Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer |
Concentration | lot specific |
Purification | Affinity purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | CD55 molecule (Cromer blood group) |
Database Link | |
Background | The 143-30 monoclonal antibody reacts with human CD55, the 64-73 kDa molecule also known as DAF (Decay-Accelerating Factor). CD55 is a GPI-anchored single chain glycoprotein expressed on all cells in contact with serum including all hematopoietic cells and vascular endothelium; a soluble form of CD55 is also present in plasma and body fluids. CD55 is thought to play a role in the protection of cells from the damage by autologous complement via prevention of the amplification steps of the complement cascade. Antibodies against CD55 are mitogenic in the presence of phorbol esters. |
Synonyms | CR; CROM; DAF; TC |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Complement and coagulation cascades, Hematopoietic cell lineage, Viral myocarditis |
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