Cd86 Rat Monoclonal Antibody [Clone ID: GL1]

CAT#: TA320296

Rat Anti-Mouse CD86 (B7-2) Purified (100 ug)


USD 205.00

2 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name GL1
Applications FC
Recommended Dilution Flow, IHC, Functional Assay, IP
Reactivities Mouse
Host Rat
Clonality Monoclonal
Formulation Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration lot specific
Purification Affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name CD86 antigen
Background The GL1 monoclonal antibody reacts with mouse CD86, an ~80 kDa surface receptor also known as B7-2. CD86 & CD80 are members of the B7 family of costimulatory molecules. CD86 is expressed at low level on B cells, macrophages, and dendritic cells and is upregulated on B cells through a variety of surface stimuli including the BCR complex, CD40 and some cytokine receptors. CD86 is also expressed by activated mouse T cells and thioglycolate-elicited peritoneal cells. In addition to CD80 (B7-1), CD86 is a counter-receptor for the T cell surface molecules CD28 and CD152 (CTLA-4). This interaction plays a critical role in T-B crosstalk, T cell costimulation, autoantibody production and Th2-mediated Ig production. The kinetics of upregulation of CD86 upon stimulation, supports its major contribution during the primary phase of an immune response.
Synonyms B7-2; B70; BU63; CD28LG2; FUN-1; LAB72; MGC34413
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.