Cd9 Rat Monoclonal Antibody [Clone ID: eBioKMC8 (KMC8)]

CAT#: TA320302

Rat Anti-Mouse CD9 Purified (100 ug)

Product Images

Staining of C57Bl/6 bone marrow cells with 0.5 ug of Rat IgG2a Isotype Control Purified (open histogram) or 0.5 ug of Anti-Mouse CD9 Purified (filled histogram) followed by Anti-Rat IgG PE. Cells in the large scatter population were used for analysis.

Specifications

Product Data

• Clone Name: eBioKMC8 (KMC8)
• Applications: FC
• Recommended Dilution: Flow, WB
• Reactivities: Mouse
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: CD9 antigen
• Database Link:
  NP_031683
  Entrez Gene 12527 Mouse
  UniProt ID P40240
• Background: The eBioKMC8 monoclonal antibody reacts with mouse CD9, a 24 kDa member of the transmembrane 4 superfamily. This family is characterized by the presence of four hydrophobic domains spanning the cell membrane and short N- and C-terminal cytoplasmic domains. CD9 is expressed by several cell types including monocytes, macrophages, platelets, early B cells, activated B and T cells, dendritic cells, eosinophils, basophils, endothelial cells, myoblasts and neuroblasts. On T cells, CD9 functions as a co-stimulatory molecule on na?ve T cells. Furthermore, CD9 is expressed in oocytes, and CD9-deficiency results in sterility caused by defective gamete fusion. In mouse macrophages, CD9 functionally associates with FcγRs to modify signals for phagocytosis and inflammatory responses. In mouse B cells, it was discovered that CD9 is a marker for marginal zone B cells, B1 cells, and plasma cells. In dendritic cells, recently it was demonstrated that CD9 facilitates the association of heterologous MHC II molecules. The level of CD9 expression is subject to donor variability.
• Synonyms: 5H9; BA2; BTCC-1; DRAP-27; GIG2; MIC3; MRP-1; OTTHUMP00000041576; P24; Tetraspanin-29; Tspan-29; TSPAN29