Cdh5 Rat Monoclonal Antibody [Clone ID: eBioBV13 (BV13)]

CAT#: TA320307

Rat Anti-Mouse CD144 (VE-Cadherin) Purified (50 ug)

Product Images

Staining of bEnd.3 cell line with 0.5 ug of Rat IgG1 K Isotype Control Purified (open histogram) or 0.5 ug of Anti-Mouse CD144 (VE-Cadherin) Purified (filled histogram) followed by F (ab')2 Anti-Rat IgG PE. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: eBioBV13 (BV13)
• Applications: FC
• Recommended Dilution: Flow, IHC, Functional Assay, IP, WB
• Reactivities: Mouse
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cadherin 5
• Database Link:
  NP_033998
  Entrez Gene 12562 Mouse
  UniProt ID P55284
• Background: The BV13 monoclonal antibody reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120 kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM) have the potential to give rise to hematopoietic cells.
• Synonyms: 7B4; CD144; FLJ17376; VE-cadherin