IL3RB (CSF2RB) Mouse Monoclonal Antibody [Clone ID: 1C1]

CAT#: TA320316

Mouse Anti-Human CD131 Purified (100 ug)

Specifications

Product Data

• Clone Name: 1C1
• Recommended Dilution: Flow, IP, WB
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: colony stimulating factor 2 receptor beta common subunit
• Database Link:
  NP_000386
  Entrez Gene 1439 Human
  UniProt ID P32927
• Background: The 1C1 monoclonal antibody reacts with the human CD131 molecule, also known as the common β subunit (βC). The common β subunit associates with the specific α subunits of IL-3 receptor, IL-5 receptor and GM-CSF receptor to form high affinity receptors for these cytokines. These cytokine receptors are expressed by neutrophils, eosinophils, monocytes, endothelial cells, fibroblasts and hematopoietic progenitor cells and play a crucial role in growth/activation of eosinophils and in the inflammatory response.
• Synonyms: CD131; CDw131; IL3RB; IL5RB; SMDP5

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Apoptosis, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway