CD23 (FCER2) Mouse Monoclonal Antibody [Clone ID: EBVCS2]

CAT#: TA320329

Mouse Anti-Human CD23 Purified (100 ug)

Product Images

Staining of normal human peripheral blood cells with 0.5 ug of Mouse IgG1 kappa Isotype Control Purified (open histogram) or 0.25ug of Anti-Human CD23 Purified (filled histogram) followed by Anti-Mouse IgG FITC. Cells in the lymphocyte gate were used for analysis.

Specifications

Product Data

• Clone Name: EBVCS2
• Applications: FC
• Recommended Dilution: Flow, IHC
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Fc fragment of IgE receptor II
• Database Link:
  NP_001993
  Entrez Gene 2208 Human
  UniProt ID P06734
• Background: The EBVCS2 monoclonal antibody reacts with human CD23, a 45 kDa type II transmembrane glycoprotein. CD23 is expressed on mature B cells, mantle zone B cells, follicular dendritic cells and at low levels on T, NK, langerhans cells and platelets. Expression of CD23 is upregulated upon B cell activation, and soluble forms of the antigen have been reported to be biologically active. CD23 is a low affinity receptor for IgE and is thought to play a role in the regulation of IgE response and B cell activation. CD21 and the alpha subunit of CD11b and CD11c bind to CD23.
• Synonyms: BLAST-2; CD23; CD23A; CLEC4J; FCE2; IGEBF

Reference Data

• Protein Families: Secreted Protein, Transmembrane
• Protein Pathways: Hematopoietic cell lineage