HLA-DRA Mouse Monoclonal Antibody [Clone ID: LN3]

CAT#: TA320345

Mouse Anti-Human HLA-DR Purified (100 ug)

Product Images

Staining of normal human peripheral blood cells with 0.125 ug of Purified Mouse IgG2b Isotype Control (open histogram) or 0.125 ug of Anti-Human HLA-DR Purified) (filled histogram) followed by Anti-Mouse IgG FITC. Cells in the lymphocyte gate were used for analysis.

Specifications

Product Data

• Clone Name: LN3
• Applications: FC
• Recommended Dilution: Flow, IHC
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: major histocompatibility complex, class II, DR alpha
• Database Link:
  NP_061984
  Entrez Gene 3122 Human
  UniProt ID P01903
• Background: The LN3 mAb reacts with the human major histocompatibility complex (MHC) class II, HLA-DR. HLA-DR is expressed on the surface of human antigen presenting cells (APC) including B cells, monocytes, macrophages, DCs, and activated T cells. HLA-DR is a heterodimeric transmembrane protein composed of α and β subunits and plays an important role in the presentation of peptides to CD4+ T lymphocytes.
• Synonyms: HLA-DRA1; MLRW

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Allograft rejection, Antigen processing and presentation, Asthma, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Hematopoietic cell lineage, Systemic lupus erythematosus, Type I diabetes mellitus, Viral myocarditis