Icam2 Rat Monoclonal Antibody [Clone ID: 3C4 (mIC2/4)]

CAT#: TA320350

Rat Anti-Mouse CD102 (ICAM-2) Purified (100 ug)

Product Images

Staining of C57BL/6 splenocytes with 0.125 ug of Rat IgG2a kappa Isotype Control Purified (blue histogram) or 0.125 ug of Anti-Mouse CD102 (ICAM-2) Purified (purple histogram) followed by Anti-Rat IgG Biotin and Streptavidin PE. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: 3C4 (mIC2/4)
• Applications: FC
• Recommended Dilution: Flow, IHC, IP
• Reactivities: Mouse
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: intercellular adhesion molecule 2
• Database Link:
  NP_034624
  Entrez Gene 15896 Mouse
  UniProt ID P35330
• Background: The monoclonal antibody 3C4 (mIC2/4) recognizes mouse CD102, also known as intercellular adhesion molecule-2 (ICAM-2). CD102, a member of the Immunoglobulin superfamily of receptors with 2 extracellular Ig domains, binds LFA (CD11a/CD18) and Mac-1 (CD11b/CD18), thereby mediating cellular interactions to lymphocytes. CD102 plays a role in NK cytotoxicity and migration, and lymphocyte recirculation. Expression of CD102 is found on most lymphocytes, monocytes and platelets. The 3C4 (mIC2/4) antibody blocks interaction of lymphocytes with antigen presenting cells.
• Synonyms: CD102; ICAM-2