ICAM2 Mouse Monoclonal Antibody [Clone ID: CBRIC2/2]

CAT#: TA320351

Mouse Anti-Human CD102 (ICAM-2) Purified (100 ug)

Product Images

Staining of normal human peripheral blood cells with 0.06 ug of Mouse IgG2a kappa Isotype Control Purified (open histogram) or 0.06 ug of Anti-Human CD102 (ICAM-2) Purified (filled histogram) followed by F (ab')2 Anti-Mouse IgG PE. Cells in the monocyte gate were used for analysis.

Specifications

Product Data

• Clone Name: CBRIC2/2
• Applications: FC
• Recommended Dilution: Flow, IHC, Functional Assay, IP, WB
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: intercellular adhesion molecule 2
• Database Link:
  NP_000864
  Entrez Gene 3384 Human
  UniProt ID P13598
• Background: The CBRIC2/2 monoclonal antibody reacts with human ICAM-2 (CD102). ICAM-2 is a 55-65 kD transmembrane glycoprotein possessing 2 extracellular Ig domains, a single transmembrane domain, and a short 26-amino acid cytoplasmic domain. ICAM-2 is expressed on most leukocytes, and is strongly expressed on vascular endothelial cells. ICAM-2 is a ligand of integrin CD11a/CD18 (LFA-1), and also has been reported to bind integrin CD11b/CD18 (Mac-1). ICAM-2 is an intercellular adhesion molecule involved in lymphocyte homing to sites of inflammation. The CBRIC2/2 antibody has been reported to have blocking activity.
• Synonyms: CD102

Reference Data

• Protein Families: ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Natural killer cell mediated cytotoxicity