IFNGR2 Mouse Monoclonal Antibody [Clone ID: NIB42]

CAT#: TA320356

Mouse Anti-Human IFN gamma Purified (50 ug)

Specifications

Product Data

• Clone Name: NIB42
• Recommended Dilution: ELISA
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interferon gamma receptor 2 (interferon gamma transducer 1)
• Database Link:
  NP_005525
  Entrez Gene 3460 Human
  UniProt ID P38484
• Background: The NIB42 antibody reacts with human interferon-gamma (IFN-γ). The NIB42 antibody is a neutralizing antibody. IFN-γ is an ~20 kDa factor produced by activated T, B and NK cells and is an anti-viral and anti-parasitic cytokine. IFN-γ in synergy with other cytokines, such as TNF-α, inhibits proliferation of normal and transformed cells. Immunomodulatory effects of IFN-γ are exerted on a wide range of cell types expressing the high affinity receptors for IFN-γ. Glycosylation of IFN-γ does not affect its biological activity.
• Synonyms: AF-1; IFGR2; IFNGT1; IMD28

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity