Il1a Hamster Monoclonal Antibody [Clone ID: ALF-161]

CAT#: TA320364

Hamster Anti-Mouse IL-1 alpha Purified (50 ug)

Product Images

Mouse splenocytes (500,000 cells per well) were activated with LPS (1 ug/ml) for 48 hrs in mouse IL-1 alpha ELISPOT assay. Control well is medium alone.

Specifications

Product Data

• Clone Name: ALF-161
• Applications: ELISA
• Recommended Dilution: ELISA
• Reactivities: Mouse
• Host: Hamster
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interleukin 1 alpha
• Database Link:
  NP_034684
  Entrez Gene 16175 Mouse
  UniProt ID P01582
• Background: The ALF-161 antibody reacts with mouse interleukin-1α (IL-1α). Mouse IL-1α, also called Lymphocyte Activating Factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), and Mononuclear Cell Factor (MCF), is a 17 kDa factor produced by a wide variety of cells, including macrophages, dendritic cells, T and B cells. IL-1α is mostly cell-associated, with 23% amino acid homology with IL-1β. The immune regulatory role of IL-1α is exerted on a wide range of cells including lymphocytes, epithelial cells and fibroblasts. In vivo, it induces hypotension, fever, and acute phase response.
• Synonyms: hematopoietin-1; IL-1A; IL1; IL1-ALPHA; IL1F1; OTTHUMP00000203692; pro-interleukin-1-alpha