IL1 beta (IL1B) Mouse Monoclonal Antibody [Clone ID: CRM56]

CAT#: TA320366

Mouse Anti-Human IL-1 beta Purified (50 ug)

Product Images

Staining of human peripheral blood mononuclear cells stimulated with LPS in the presence of Brefeldin A for 4 hours with Anti-Human CD14 PE (left) or Anti-Human CD14 FITC (right) followed by intracellularly Anti-Human IL-1 beta PE.

Specifications

Product Data

• Clone Name: CRM56
• Applications: FC
• Recommended Dilution: Flow, ELISA, Functional Assay
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Formulation: PBS, 0.09% sodium azide.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interleukin 1 beta
• Database Link:
  NP_000567
  Entrez Gene 3553 Human
  UniProt ID P01584
• Background: The CRM56 antibody reacts with human and baboon interleukin-1 beta; (IL-1 beta). IL-1 beta is a 17 kDa factor secreted primarily by monocytes. IL-1 has effects on T-helper cells, inducing IL-2 secretion and expression of IL-2 receptors. IL-1 has effects on B cells, promoting cell proliferation and immunoglobulin synthesis.
• Synonyms: IL-1; IL1-BETA; IL1F2

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Alzheimer's disease, Apoptosis, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Graft-versus-host disease, Hematopoietic cell lineage, MAPK signaling pathway, NOD-like receptor signaling pathway, Prion diseases, Toll-like receptor signaling pathway, Type I diabetes mellitus