IL2 Receptor alpha (IL2RA) Mouse Monoclonal Antibody [Clone ID: BC96]

CAT#: TA320368

Mouse Anti-Human CD25 Purified (100 ug)

Product Images

Staining of PHA stimulated human PBMC with Anti-Human CD25 PE. Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: BC96
• Applications: FC
• Recommended Dilution: Flow
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interleukin 2 receptor subunit alpha
• Database Link:
  NP_000408
  Entrez Gene 3559 Human
  UniProt ID P01589
• Background: The BC96 monoclonal antibody reacts with human CD25, the 55 kDa interleukin-2 receptor α chain (IL-2Rα). CD25 is expressed by early progenitors of T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor β chain) and CD132 (common γ chain) to form the high affinity IL-2 receptor. CD25 plays a role in lymphocyte differentiating and activation/proliferation.
• Synonyms: CD25; IDDM10; IL2R; p55; TCGFR

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Jak-STAT signaling pathway