IL3RA Mouse Monoclonal Antibody [Clone ID: 6H6]

CAT#: TA320370

Mouse Anti-Human CD123 Purified (100 ug)

Product Images

Staining of TF-1 cell line with Mouse IgG1 kappa Isotype Control Purified (open histogram) or Anti-Human CD123 Purified (filled histogram) followed by F (ab')2 Anti-Mouse IgG PE. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: 6H6
• Applications: FC
• Recommended Dilution: Flow, IHC
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interleukin 3 receptor subunit alpha
• Database Link:
  NP_002174
  Entrez Gene 3563 Human
  UniProt ID P26951
• Background: The 6H6 monoclonal antibody reacts with human CD123, the α chain of the IL-3 receptor. This 60-70 kDa transmembrane protein binds to IL-3 with low affinity by itself, and when associated with CD131 (common β chain) binds IL-3 with high affinity. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, and megakaryocytes.
• Synonyms: CD123; hIL-3Ra; IL3R; IL3RAY; IL3RX; IL3RY

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Apoptosis, Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway