Integrin alpha E (ITGAE) Mouse Monoclonal Antibody [Clone ID: B-ly7]

CAT#: TA320382

Mouse Anti-Human CD103 (Integrin alpha E) Purified (100 ug)

Product Images

Staining of 3-day PHA-stimulated normal human peripheral blood cells with 0.25 ug of Mouse IgG1 kappa Isotype Control Purified (open histogram) or 0.25 ug of Anti-Human CD103 (Integrin alpha E) Purified (filled histogram) followed by Anti-Mouse IgG FITC. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: B-ly7
• Applications: FC
• Recommended Dilution: Flow, IHC
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: integrin subunit alpha E
• Database Link:
  NP_002199
  Entrez Gene 3682 Human
  UniProt ID P38570
• Background: The B-Ly7 monoclonal antibody reacts with human CD103, the αE integrin. CD103 non-covalently associates with integrin β7. CD103 is expressed mainly on intraepithelial lymphocytes and a small subset of peripheral lymphocytes. CD103 is also expressed by hairy cell leukemia (HCL) and by some chronic B cell lymphocytic leukemias. In vitro stimulation of human T cells with mitogens induces upregulation of CD103. Epithelial cell antigen, E-cadherin, binds to CD103 and mediates homing of lymphocytes to the intestinal epithelium.
• Synonyms: CD103; HUMINAE

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Regulation of actin cytoskeleton