CD11a (ITGAL) Mouse Monoclonal Antibody [Clone ID: HI111]

CAT#: TA320383

Mouse Anti-Human CD11a Purified (100 ug)

Product Images

Staining of normal human peripheral blood cells with Anti-Human CD11a FITC.

Specifications

Product Data

• Clone Name: HI111
• Applications: FC
• Recommended Dilution: Flow, IHC, Functional Assay
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: integrin subunit alpha L
• Database Link:
  NP_002200
  Entrez Gene 3683 Human
  UniProt ID P20701
• Background: The HI111 monoclonal antibody reacts with human CD11a, the 180 kDa integrin αL, also known as the lymphocyte function associated antigen-1 (LFA-1) α chain. LFA-1, formed by non-covalent association of CD11a with CD18 (integrin β2), serves as an important adhesion molecule involved in lymphocyte and granulocyte function. CD54 (ICAM-1), CD102 (ICAM-2), and CD50 (ICAM-3) are ligands for LFA-1. CD11a is expressed by all leukocytes.
• Synonyms: CD11A; LFA-1; LFA1A

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Regulation of actin cytoskeleton, Viral myocarditis