Itgal Rat Monoclonal Antibody [Clone ID: M17/4]

CAT#: TA320384

Rat Anti-Mouse CD11a Purified (50 ug)

Product Images

Staining of mouse splenocytes with Anti-Mouse CD11a FITC (left) and PE (right). Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: M17/4
• Applications: FC
• Recommended Dilution: Flow, IHC, Functional Assay, IP
• Reactivities: Mouse
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: integrin alpha L
• Database Link:
  NP_032426
  Entrez Gene 16408 Mouse
• Background: The M17/4 monoclonal antibody reacts with mouse CD11a, the 180 kDa integrin alpha L, also known as the lymphocyte function associated antigen-1 (LFA-1) alpha chain. LFA-1, formed by non-covalent association of CD11a with CD18 (integrin beta 2), serves as an important adhesion molecule involved in lymphocyte and granulocyte function. CD54 (ICAM-1), CD102 (ICAM-2), and CD50 (ICAM-3) are ligands for LFA-1. CD11a is expressed by all leukocytes.
• Synonyms: CD11A; LFA-1; LFA-1A; LFA1A