CD11b (ITGAM) Mouse Monoclonal Antibody [Clone ID: ICRF44]

CAT#: TA320386

Mouse Anti-Human CD11b Purified (100 ug)

Product Images

Staining of normal human peripheral blood cells with Anti-Human CD11b PE. Autofluorescence is indicated by open histogram. Cells in the monocyte population were used for analysis.

Specifications

Product Data

• Clone Name: ICRF44
• Applications: FC
• Recommended Dilution: Flow, IHC, Functional Assay
• Reactivities: Baboon, Chimpanzee, Human, Rhesus
• Host: Mouse
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: integrin subunit alpha M
• Database Link:
  NP_000623
  Entrez Gene 3684 Human
  UniProt ID P11215
• Background: The ICRF44 monoclonal antibody reacts with human CD11b, a 165 kDa adhesion molecule. CD11b associated with integrin β2 (CD18) is expressed on the surface of monocytes, granulocytes, activated lymphocytes and a subset of NK cells. CD11b is a receptor for intercellular adhesion molecule family members CD54, CD102 and CD50 as well as for iC3b. These adhesions are crucial in cell-cell and cell-matrix interactions.
• Synonyms: CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Leukocyte transendothelial migration, Regulation of actin cytoskeleton