Itgam Rat Monoclonal Antibody [Clone ID: M1/70]

CAT#: TA320387

Rat Anti-Mouse CD11b Purified (100 ug)

Product Images

Staining of mouse bone marrow with Anti-Mouse CD11b FITC (left) and PE (right). Appropriate isotype controls were used (open histogram). Cells in the myeloid population were used for anaysis.

Specifications

Product Data

• Clone Name: M1/70
• Applications: FC
• Recommended Dilution: Flow, IHC, Functional Assay, IP
• Reactivities: Mouse
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: integrin alpha M
• Database Link:
  NP_032427
  Entrez Gene 16409 Mouse
• Background: The M1/70 monoclonal antibody reacts with mouse CD11b, the 165-170 kDa integrin αM. CD11b non-covalently associates with CD18 to form αMβ2 integrin (Mac-1) and binds to CD54 (ICAM-1), C3bi, and fibrinogen. Mac-1 is expressed by macrophages, NK cells, granulocytes, activated lymphocytes and mouse B-1 cells in the peritoneal cavity. M1/70 is also cross-reactive to human CD11b, and can be used for the detection of this antigen on human peripheral blood monocytes, granulocytes, and a subset of NK cells. Through interactions with its ligands, CD11b participates in adhesive cell interactions.
• Synonyms: CD11B; CR3A; MAC-1; MAC1A; MGC117044; MO1A; SLEB6