CD11c (ITGAX) Mouse Monoclonal Antibody [Clone ID: 3.9]

CAT#: TA320390

Mouse Anti-Human CD11c Purified (25 ug)

Product Images

Staining of normal human peripheral blood cells with Anti-Human CD11c FITC (left) and PE (right). Appropriate isotype controls were used (open histogram). Cells in the monocyte population were used for analysis.

Specifications

Product Data

• Clone Name: 3.9
• Applications: FC
• Recommended Dilution: Flow, IHC
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: integrin subunit alpha X
• Database Link:
  NP_000878
  Entrez Gene 3687 Human
  UniProt ID P20702
• Background: The 3.9 monoclonal antibody reacts with human CD11c, the 150 kDa integrin αX chain. CD11c non-covalently associates with β2 integrin to form the CD11c/CD18 heterodimer. This complex is expressed on monocytes, granulocytes, macrophages, NK, dendritic cells and subset of T and B lymphocytes. CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions.
• Synonyms: CD11C; SLEB6

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Regulation of actin cytoskeleton