Itgax Hamster Monoclonal Antibody [Clone ID: N418]

CAT#: TA320391

Hamster Anti-Mouse CD11c Purified (100 ug)

Product Images

Staining of mouse splenocytes with Anti-Mouse CD11c FITC (left) and PE (right), and Anti-Human/Mouse CD45R (B220) APC. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: N418
• Applications: FC
• Recommended Dilution: Flow, IHC, IP
• Reactivities: Mouse
• Host: Hamster
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: integrin alpha X
• Database Link:
  NP_067309
  Entrez Gene 16411 Mouse
  UniProt ID Q9QXH4
• Background: The N418 monoclonal antibody reacts with mouse CD11c, the integrin αX. CD11c non-covalently associates with β2 integrin to form the CD11c/CD18 heterodimer. CD11c is expressed by dendritic cells, a subset of Intestinal Intraepithelial Lymphocytes (IEL) and some activated T cells. CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions. N418 binds to CD11c on splenic dendritic cells in the T-dependent areas of mouse spleen and precipitates a 150, 90 kDa heterodimer.
• Synonyms: CD11C; SLEB6