Itgb1 Hamster Monoclonal Antibody [Clone ID: eBioHMb1-1 (HMb1-1)]

CAT#: TA320392

Hamster Anti-Mouse/Rat CD29 (Integrin beta 1) Purified (50 ug)

Product Images

Staining of C57Bl/6 thymocytes with 0.5 ug of Armenian Hamster IgG Isotype Control Purified (open histogram) or 0.5 ug of Anti-Mouse/Rat CD29 Purified (filled histogram) followed by Anti-Armenian Hamster IgG Biotin and Streptavidin PE. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: eBioHMb1-1 (HMb1-1)
• Applications: FC
• Recommended Dilution: Flow, Functional Assay, IP
• Reactivities: Mouse, Rat
• Host: Hamster
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: integrin beta 1 (fibronectin receptor beta)
• Database Link:
  NP_034708
  Entrez Gene 24511 RatEntrez Gene 16412 Mouse
  UniProt ID P09055
• Background: The eBioHMb1-1 monoclonal antibody reacts with mouse and rat CD29 (integrin beta 1), a 110-120 kDa member of the beta integrin family expressed by leukocytes, endothelial, smooth muscle and epithelial cells. CD29 binds non-covalently with the alpha integrins CD49a-f to form the VLA-1 through VLA-6 complexes, as well as with CD51. These alpha-beta integrin heterodimers are capable of mediating a variety of cellular responses including adhesion, trafficking, proliferaton and differentiation. All integrins which include CD29 bind to extracellular matrix proteins including collagen, laminin, fibronectin and vitronectin, whereas some CD29-containing integrins can also interact with cellular receptors such as VCAM-1 and MadCAM-1.
• Synonyms: CD29; FNRB; GPIIA; MDF2; MSK12; VLA-BETA; VLAB