Itgb2 Rat Monoclonal Antibody [Clone ID: M18/2]

CAT#: TA320395

Rat Anti-Mouse CD18 Purified (100 ug)

Product Images

Staining of mouse splenocytes with Anti-Mouse CD18 PE. Autofluorescence is shown via open histogram. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: M18/2
• Applications: FC
• Recommended Dilution: Flow, IHC, Functional Assay, IP, WB
• Reactivities: Mouse
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: integrin beta 2
• Database Link:
  NP_032430
  Entrez Gene 16414 Mouse
  UniProt ID P11835
• Background: The M18/2 monoclonal antibody reacts with mouse CD18, the 90-95 kDa integrin beta 2 glycoprotein. CD18 is the common β subunit that non-covalently associates with CD11a (alpha L), CD11b (alpha M) and CD11c (alpha X) to form LFA-1, Mac-1 and gp150/95. Heterodimers of CD18 and the a subunits are expressed broadly by all leukocytes with NK and T cells showing higher density of surface expression. Through the interactions of LFA-1, Mac-1 and gp150/95 with their counter-receptors, CD18 is involved in cellular adhesion and the immune response.
• Synonyms: CD18; LAD; LCAMB; LFA-1; MAC-1; MF17; MFI7; OTTHUMP00000115279; OTTHUMP00000115281; OTTHUMP00000115282